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This review summarizes how GLP 1 and dual GIP GLP 1 receptor agonists act at the cellular level and their therapeutic applications in metabolic diseases like type 2 diabetes and obesity, highlighting advances in incretin based In silico exploration of phytochemicals for GLP 1 receptor agonists for the treatment of type 2 diabetes Computational and Structural Biotechnology Reports GLP 1 Drug Savings: A Complete Guide for How to Save on Ozempic, Wegovy, and More GoodRx DOSE OF REALITY: BIG PHARMA'S GLP 1 PRICE GOUGING UNSUSTAINABLE FOR AMERICAN PATIENTS AND THE U.S. HEALTH SYSTEM CSRxP How do weight loss drugs like Wegovy work? In the latest edition of #PeriodicGraphics in C&EN we take a look at the science and history behind these drugs: https: cen.acs.org biological chemistry Periodic Graphics science weight loss 103 i2
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★★★★★ 5
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Size: 11, Color: Tan
Great fit comfortable look good
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Reviewed in the United States on May 12, 2026
★★★★★ 5
Great shoes
Size: 14 Wide, Color: Black
My shoes look good and feel good and now I’m going to purchase the brown pair I saw
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Reviewed in the United States on April 24, 2026
★★★★★ 4
Don’t buy for restaurant industry
Size: 10.5, Color: Black, Size: 10.5, Color: Black
Good looking shoes, fairly comfortable and good value based on the description shared, so I don’t feel it’s fair to rate them lower than 4 stars. I had high hopes for them based on previous reviews from others saying they wore them in the food and beverage industry that mentioned their quality and durability, however I strongly recommend looking elsewhere if you do. I purchased these to wear working in a full service upscale restaurant and in less than two months have managed to have torn the material on the middle exterior section and the bottoms of the shoes are already completely worn down. Good design, but the durability needs to be improved if they’re to hold up for that industry.
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Reviewed in the United States on July 18, 2025
★★★★★ 1
DO NOT BUY (lasted less than 7 months)
Size: 11, Color: Black, Size: 11, Color: Black
I bought these for work as a bartender in August of 2025. By December, the tops were scuffed, frayed, and peeling beyond repair, and by February, the soles were coming off. I’ve never had a pair of shoes with such low quality.
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Reviewed in the United States on April 11, 2026
★★★★★ 5
Most comfortable shoes, right out of the box!
Size: 8.5, Color: Cognac Napa Leather
Oh my! So, my ordering of shoes online has been hit or miss - 1/2 size too big or too small; too wide or not wide enough. Enter these Marc Joseph shoes… such a game changer. They fit like a glove, exceptionally comfortable, and easy to slip in and out of. I like them so much that I am shopping for another pair. So far, the size, quality, fit, feel, look, and comfort make this pair my dedicated first pick. Btw, I have been wearing them for six hours and they are still very comfortable! I highly recommend these shoes.
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Reviewed in the United States on September 28, 2025
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